Gabapentin is a gamma-aminobutyric acid (GABA) analogue, structurally related to GABA, and is used for people who are suffering from epileptic seizures and neuropathic pain. It is not recommended for people who have absence seizures, a different type of epilepsy. Gabapentin is much more commonly used in treatment of various nerve related pain conditions than for treatment of seizure disorders.
Gabapentin dosage varies with each individual, and because of the very common side effects with the initiation of treatment, the gabapentin dosage is usually started very low, and gradually titrated higher until therapeutic gabapentin dosage is achieved. It usually starts off at 100-300mg at night because its gabapentin side effects include fatigue and sleepiness. People suffering from neuropathic pain have a recommended Gabapentin dosage 600 mg three times daily, so in order to get to that gabapentin dosage a slow steady upward titration is usually required. The maximum dose is up to 4800 mg daily, though many patients take just 1800 mg an find adequate benefits at that gabapentin dosage. For people who have kidney issues the gabapentin dosage needs to be reduced as high levels of gabapentin may cause confusion and psychosis.
Gabapentin indications include diabetic peripheral neuropathy, post herpetic neuropathy in patients with herpes zoster (commonly called shingles), radicular pain from nerve root irritation both in the low back and the neck, and as an anticonvulsant drug usually in combination with another anticonvulsant for additional seizure control.
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