Metformin is a commonly used medications for the management of blood sugar in type II diabetes but metformin contraindications can make it a poor choice in some patients. Among the most important metformin contraindications are used in patients with renal insufficiency. Usually metformin is not used in men with a serum creatinine of greater than 1.5 or women with a serum creatinine greater than 1.2. The use of metformin in patients with renal insufficiency can increase chances of lactic acidosis.

Another metformin contraindication is in patients undergoing iodinated contrast studies. Patients on metformin should have their metformin discontinued prior to radiologic studies using I’d knitted contrast because of an increased incidence of acute renal failure when I’d knitted contrast studies are done in patients on metformin.

Metformin is also contraindicated in patients with diabetic ketoacidosis, lactic acidosis, dehydration, undergoing major surgery, web serious liver disease, and in patients who have a history of analogy or hypersensitivity to metformin or other medications in its class. Read up on our main page about Metformin side effects has.

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