When metformin diarrhea is simply not tolerated often an alternative medication is needed. This can sometimes be a sulfonylurea, one of the GLP 4 inhibitors or an injectable medication like Byetta or the Victoza. Occasionally insulin is needed if oral diabetes medications are not adequate to control the diabetes. It’s estimated that metformin diarrhea occurs in up to 10% of patients who use metformin although some of these patients tolerate metformin viral well enough to continue using the medication.
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